Department of Chemistry

Xavier University of Louisiana

Stassi DiMaggio, Ph.D.
Professor
Kellogg Endowed Professor of Teaching
PhD, Chemistry, University of New Orleans, 2003
B.S Biochemistry, Tulane University, 1998

Telephone Number: 504-520-5706
Room Number: NCF - Room 301J
Email Address: scdimagg@xula.edu
Courses

Organic Chemistry, Drug Design and Synthesis

Short Professional Biography

Dr. DiMaggio received a B.S. in Biochemistry from Tulane University in 1998 and a Ph.D. in Organic Chemistry from the University of New Orleans in 2003. Her dissertation research involved designing and synthesizing biologically active molecules based on natural products as well as natural product synthesis. She also enjoyed an appointment as a Visiting Professor at the University of Michigan, Ann Arbor (2005-2006) where she focused on synthesizing functionalized nanomaterials to be used in basic studies as potential drug delivery systems. She gladly joined the Xavier Chemistry Department in 2003 where she has been at home ever since and conducts research on drug delivery and gene delivery systems using modified nanomaterials. She maintains a position as a Visiting Scholar in the Chemistry Department at the U of M and is currently serving as the Louisiana Local Section of the American Chemical Society Past Chair, of which she has been an active member since 1998. She is a member of the ACS Organic and Polymer Divisions and the Louisiana Cancer Research Consortium. She serves as the Phi Lambda Upsilon Chemistry Honor Society advisor. She is also the recipient of the 2012 Norman C. Francis Excellence in Teaching Award, the Alan Berman Research Publication Award from the Naval Research Laboratory and the Kellogg II Endowed Professor of Teaching award.

Research Interest

Targeted Drug Delivery
Non-viral gene delivery
Nanomaterial synthesis and characterization

Current Grant Support

NSF EPSCoR Track 2
NIH BUILD

Recent Publications
  1. Synthesis, Characterization, and In Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers Kevin J. Landmark, Stassi DiMaggio, Jesse Ward, Stefan Vogt, Seungpyo Hong, Alina Kotlyar, James E. Penner-Hahn, James R. Baker, Jr., Mark M. Banaszak Holl, Bradford G. Orr, ACS Nano (2008), 2(4), 773-783.
  2. Interactions of Poly(amidoamine) Dendrimers with Survanta Lung Surfactant: The Importance of Lipid Domains. Erickson, Blake; DiMaggio, Stassi; Mullen, Douglas; Kelly, Christopher; Leroueil, Pascale; Berry, Stephanie; Baker, James; Orr, Bradford; Banaszak Holl, Mark. Langmuir (2008), 24(19), 11003-11008.
  3. Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes. Chen, Jiumei; Blunt, Jessica; Putchakayala, Krishna; Panama, Brian; Khan, Damian; Hong, Seungpyo; Mullen, Douglas; DiMaggio, Stassi; Som, Abhigyan; Tew, Greg; Lopatin, Anatoli; Baker, James; Orr, Bradford; Banaszak Holl, Mark. Journal of Physical Chemistry B (2009), 113(32), 11179-11185.
  4. Enantioselective Syntheses of Both Enantiomers of Noranabasamine. Miao, Lei; Di Maggio, Stassi C.; Shu, Hong; Trudell, Mark L. Organic Letters (2009), 11(7), 1579-1582.
  5. Ir-Catalyzed N-Heterocyclization for Enantioselective Synthesis of Noranabasamine. Miao, Lei; Di Maggio, Stassi C.; Shu, Hong; Trudell, Mark L. Synfacts (2009), 7, 773.
  6. Hydroxyarylketones via Ring-Opening of Lactones with Aryllithium Reagents: An Expedient Synthesis of (±)-Anabasamine. Miao, Lei; DiMaggio, Stassi C.; Trudell, Mark L. Synthesis, Synthesis 2010; 2010: 91-97.
  7. Mullen DG, McNerny DQ, Desai A, Cheng XM, Dimaggio SC, Kotlyar A, Zhong Y, Qin S, Kelly CV, Thomas TP, Majoros I, Orr BG, Baker JR, Banaszak Holl MM Related Articles. Design, Synthesis, and Biological Functionality of a Dendrimer-Based Modular Drug Delivery Platform. Bioconjug Chem. 2011, (22) pp 679-689.
  8. Kevin J. Landmark, Stassi DiMaggio, Jesse Ward, Christopher Kelly, Stefan Vogt, Seungpyo Hong, Alina Kotlyar, Andrzej Myc, Thommey P. Thomas, James E. Penner-Hahn, James R. Baker, Jr., Mark M. Banaszak Holl and Bradford G. Orr. Synthesis, Characterization, and in Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers. ACS Nano Virtual Special Issue on Drug Delivery, 2011, 1 (2).
  9. Boeneman, Kelly; Delehanty, James; Blanco-canosa, Juan; Susumu, Kimihiro; Stewart, Michael; Oh, Eunkeu; Huston, Alan; Dawson, Glyn; Ingale, Sampat; Walters, Ryan; Domowicz, Miriam; Deschamps, Jeffrey; Algar, W.; DiMaggio, Stassi; Manono, Janet; Spillmann, Christopher; Thompson, Darren; Jennings, Travis; Dawson, Philip; Medintz, Igor.  Selecting Improved Peptidyl Motifs for Cytosolic Delivery of Disparate Protein and Nanoparticle Materials. ACS Nano. (2013), 7(5), 3778-3796.
  10. 10. Dougherty, C. A., Furgal, J. C., van Dongen, M. A., Goodson, T., Banaszak Holl, M. M., Manono, J. and DiMaggio, S.* (2014), Isolation and Characterization of Precise Dye/Dendrimer Ratios. Chem. Eur. J., (2014), 20(16), 4638-4645
  11. Generation 3 PAMAM Dendrimer TAMRA Conjugates Containing Precise Dye/Dendrimer Ratios.  Janet Manono, Casey A. Dougherty, Kirsten Jones, Joshua DeMuth, Mark M. Banaszak Holl and Stassi DiMaggio* Materials Today Communication, 2015, 4. 86-92.
  12. Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study.  Pascale R. Leroueil, Stassi DiMaggio, Abagail N. Leistra, Craig D. Blanchette, Christine Orme, Kumar Sinnah, Bradford G. Orr, and Mark M. Banaszak Holl.  Atomic Force Pulling  Journal of Physical Chemistry B, 2015, 119 (35), 11506–11512
  13. Janet Manono@, Casey A. Dougherty, Kirsten JonesXU, Joshua DeMuth, Mark M. Banaszak Holl and Stassi DiMaggio*,^,#. Generation 3 PAMAM Dendrimer TAMRA Conjugates Containing Precise Dye/Dendrimer Ratios. Materials Today Communication, 2015, 4. 86-92.
  14. Sriram Vaidyanathan, Milan Kaushik, Casey Dougherty, Rahul Rattan, Sascha N. Goonawardena, Mark M Banaszak Holl, Janet Monano@, and Stassi DiMaggio*,^,#. Increase in Dye:Dendrimer Ratio Decreases Cellular Uptake of Neutral Dendrimers in RAW cells.  ACS Biomater. Sci. Eng., 2016, 2 (9), pp 1540–1545.
  15. DiMaggio, Stassi. "Xavier University: Routinely Beating the Odds”, Diversity in the Scientific Community. Ed. Donna Nelson and H.N. Cheng. Washington D.C.  American Chemical Society, in press.

Department of Chemistry

504-520-5082